Statin side effects can cause some to choose risk over discomfort but it is possible to reduce, if not reverse, the side effects of statins. It is no coincidence that these are the same “side effects” listed for statins; the depletion of CoQ10 when on statin drugs can lead to a shortage of energy for nerve cells and heart muscle cells, as well as a shortage of ATP needed for muscle recovery and repair. The study checked for maximal exercise capacity, use of muscle fuel during exercise, muscle function, and mitochondrial energy metabolism. The article goes on to say that statin-induced muscle damage can occur within a week of starting treatment or after four years. In absolute terms, this increase in muscle pain is 100 times greater than that reported in clinical trials…” Some health professionals acknowledge that there can be cognitive dysfunction for certain patients. A. Statin medications such as atorvastatin, rovustatin and simvastatin - the most commonly used statins - … So, the absence of damaging changes in muscle function and performance would not apply to those who were already statin users, and especially not those with symptoms. (adsbygoogle = window.adsbygoogle || []).push({}); Lowering cholesterol levels reduces risk of heart attack or stroke and many people may be prescribed statins for the rest of their lives, according to the Mayo clinic. Since the effect of statins is on all the muscles in the body and felt most in the skeletal muscles being used during activity, any kind of PEMF may help, but whole body PEMFs, which cover a majority of the body muscles may be the most beneficial. Persistent muscle pain and dark urine may point to rhabdomyolysis, a condition that can cause kidney failure and death. Dr. Rash or flushing is a possible side effect of statin use, especially if you also take niacin. Biofizika. All Rights Reserved, Black Friday 10% Sale! Statins are used to lower cholesterol into what are considered to be optimal ranges. Otherwise, small area PEMFs may still be able to help with smaller areas which may be affected most. Muscle aches that are statin side effects won’t be relieved by over-the-counter pain relievers. Delayed muscle soreness after exercise has been shown to be improved by PEMFs. Muscle myopathy can be a frustrating side effect of statin therapy, but you should never stop taking your medication for any length of time without talking to your doctor first. Muscular strength development by electromagnetic stimulation. (Surma; Eldashev; De Carlo). You should determine if it is your prescription and not other factors that are causing muscle aches before making medication changes. They do this through a number of mechanisms, including nerve stimulation, mainly by increasing energy supply in the muscle, improving circulation, reducing swelling in the muscles after activity, stimulating stem cell production, and probably other actions as well. ATP production capacity was lowest in the symptomatic group of statin users and highest in control subjects. The entire contents of this website are based on the opinions of Dr. William Pawluk, MD, unless otherwise noted. Han TR, Shin HI, Kim IS. ... B vitamins can help reverse statin-induced neuropathy. These symptoms can be an indication of myopathy and muscle damage. At the very least, they can increase their activity and ability to exercise, while still taking their statins. Jeon HS, Kang SY, Park JH, Lee HS. It is intended only as a sharing of knowledge and information based on the research and experience of Dr. Pawluk and his community.If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare professional before using products presented on this website.This content may not be copied, in full or in part, without the express written consent of Dr. Pawluk. In order to determine if your muscle aches are a statin side effect, ask your doctor about taking a break from your medication for 10 to 14 days. Cholesterol is a fundamental molecule made by the body for many health maintaining purposes, including helping to fight infection, reducing cancer rates, producing coenzyme Q 10, vitamin D, the sex hormones and the body’s own natural cortisone. 2012 Nov;18(21-22):2248-58. )After a year I had muscle pain. Talk to your doctor about changing your dosage, trying another statin or trying another cholesterol-lowering medication. Effects of pulsed electromagnetic field therapy on delayed-onset muscle soreness in biceps brachii. Magnetic stimulation of the quadriceps femoris muscle: comparison of pain with electrical stimulation. Most have no issues, but some people report muscle pain and weakness while on the drug. Best Answers. In our experience with visitors to this website, it can even occur after more than a decade of use. Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). And, most people tend to follow their doctors’ advice and take the statin medicine as prescribed. Statin side effects can cause some to choose risk over discomfort but it is possible to reduce, if not reverse, the side effects of statins. And a daily dose of 1,000 to 2,000 IU is safe for everyone. What you can do about muscle pain from statins. Your doctor should test for rhabdomyolysis if you develop persistent muscle pain and weakness accompanied by dark urine. Statins Affect Skeletal Muscle Performance: Evidence for Disturbances in Energy Metabolism. Alzheimer's and cardiovascular disease share common…, Air pollution and noise increase risk for heart attacks, Novel strategy appears to protect retina when…, Seeing shapeshifting receptors at work could yield new drugs, Scientists identify cellular gene signatures for…, A healthy lifestyle cuts stroke risk, irrespective…, Hypnotherapy could help relieve irritable bowel…, Type 2 diabetes screening in community pharmacies could increase early diagnosis, Hormone therapy helps strengthen brain connections in transgender women, How does estrogen protect bones? Gorodnichev RM, Beliaev AG, Pivovarova EA, et al. One in four Americans, ages 45 and older or almost 32 million take a statin. Bioelectromagnetics. (Bakar) The PEMF induces controlled activation of nerves in the stimulation area and hence muscle contractions. Circulation. After an angioplasty about 2 years ago , I was put on 40 mg of statins. Mitochondrial density, in turn, was directly related to exercise capacity, VO2peak. For various reasons, people who are taking these drugs may not be able to stop them, following doctors’ orders. © 2003 – 2020 William Pawluk, M.D., M.Sc. ( Blood clot in my LAD after working out at the gym! In addition, statins impact calcium balance in the muscles which can also contribute to cramps and muscle pain. The information on this website is not intended to replace the relationship between you and your medical doctor and is not intended as medical advice. A key component of treatment for rhabdomyolysis is aggressive hydration, sometimes accompanied by use of a diuretic to flush the kidneys. More muscle energy was required in asymptomatic statin users at rest and this extra demand was still present in people with muscle damage after stopping statin therapy. The mitochondrial energy generating capacity of the asymptomatic statin users was reduced even compared to healthy people. Keep track of any new symptoms that develop when you begin taking a statin, and report them to your doctor. Allard NAE, Schirris TJJ, Verheggen RJ, et al. Effect of low-intensity magnetic fields on the development of satellite muscle cells of a newborn rat in the primary culture. Muscle pain is the most frequent and troubling side effect reported with statin use. Nonionizing radiation as a noninvasive strategy in regenerative medicine: the effect of Ca(2+)-ICR on mouse skeletal muscle cell growth and differentiation. It is associated with cardiovascular disease but many believe that it is not the cause. AAOS: supplement use low in patients with osteoporosis, hip fracture. Also, high intensity PEMFs can generate very powerful muscle contractions with much less discomfort than electrical stimulation. However, this study only recruited individuals who had never taken statins. Symptomatic statin users had 69% of the ATP of the controls and asymptomatic statin users had 81%. Ask you doctor about it before taking coenzyme Q10 to determine if it might interact with any other medications you are taking. Most doctors prescribe them like candy, not really being convinced that there are significant problems with their use. See more on this molecule at this. Muscle pain is the most frequent and troubling side effect reported with statin use. Statin side effects may increase when you take statins in combination with medications for irregular heart rhythms, antidepressants or drugs that suppress the immune system. For example, the Effect of Statins on Skeletal Muscle Function and Performance (STOMP) trial is, to our knowledge, the only randomized, double-blind clinical trial that has examined aerobic exercise performance and muscle strength before and after treatment with placebo or high-dose atorvastatin (STOMP) (Parker). About identifying possible interactions that could be contributing to side effects is extremely low, report. 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