Asia Pac J Clin Nutr 2006;15(2):267-274. Toxicological evaluation of fenugreek seeds: a long term feeding experiment in diabetic patients. Yao Xue.Xue.Bao. J Med Food 2009;12(5):1046-1049. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Use of fenugreek seed powder in the management of non-insulin dependent diabetes mellitus. Hypoglycaemic effect of fenugreek seeds in non-insulin dependent diabetic subjects. Srinivasan, S., Koduru, S., Kumar, R., Venguswamy, G., Kyprianou, N., and Damodaran, C. Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells. Phytother Res. Loss Of Appetite. Effect of soluble dietary fibre fraction of Trigonella foenum graecum on glycemic, insulinemic, lipidemic and platelet aggregation status of Type 2 diabetic model rats. Zuppa, A. Nutr Res 2009;29(1):49-54. 2014 Sep;66(7):293-300. J Allergy Clin Immunol Pract. Stop using fenugreek and call your healthcare provider at once if you have: symptoms of severe hypoglycemia: extreme weakness, confusion, tremors, sweating, fast heart rate, trouble speaking, nausea, vomiting, rapid breathing, fainting, and seizure (convulsions); or. Lambert J, Cormier J. World J Gastroenterol. (check all that apply). Acta Pol.Pharm. J Pharm Pharm Sci 2010;13(2):162-174. Blanco, J. Dietary folate and depressive symptoms are associated in middle-aged Finnish men. View abstract. Int J Mol.Med 2003;11(1):23-26. Abdo MS, al-Kafawi AA. View abstract. Belguith-Hadriche, O., Bouaziz, M., Jamoussi, K., El Feki, A., Sayadi, S., and Makni-Ayedi, F. Lipid-lowering and antioxidant effects of an ethyl acetate extract of fenugreek seeds in high-cholesterol-fed rats. Sharma RD, Raghuram TC. Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. Prostaglandins Leukot Essent Fatty Acids 1997;56:379-84. J AOAC Int 2007;90(2):358-363. Nathan J, Panjwani S, Mohan V, Joshi V, Thakurdesai PA. Efficacy and safety of standardized extract of Trigonella foenum-graecum L seeds as an adjuvant tocL-Dopa in the management of patients with Parkinson's disease. Ann.Pharmacother. Treatment of Men Infertility using Low doses of Fenugreek Oil Extract. N Engl J Med 1999;341:769.. View abstract. Effect of fenugreek fiber on satiety, blood glucose and insulin response and energy intake in obese subjects. Fenugreek might decrease blood sugar. Studies on some Egyptian foods. Part 1: Biochemical and biological evaluation. In vivo effect of Trigonella foenum graecum on the expression of pyruvate kinase, phosphoenolpyruvate carboxykinase, and distribution of glucose transporter (GLUT4) in alloxan-diabetic rats. Diabetes medications are also used to lower blood sugar. Pharmacotherapy 2001;21:509-12. The day of the yam. View abstract. Zhongguo Zhong.Yao Za Zhi. Younesy S, Amiraliakbari S, Esmaeili S, Alavimajd H, Nouraei S. Effects of fenugreek seed on the severity and systemic symptoms of dysmenorrhea. An evaluation of hypocholesterolemic factor of fenugreek seeds (T foenum graecum) in rats. Rai, A., Mohapatra, S. C., and Shukla, H. S. Correlates between vegetable consumption and gallbladder cancer. A clinical study. Li, F., Fernandez, P. P., Rajendran, P., Hui, K. M., and Sethi, G. Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. J Midwifery Womens Health 2004;49(2):151-154. Madar Z, Thorne R. Dietary fiber. 2011;61(11):1116-1120. Eur J Cancer Prev. Hypolipidaemic effect of fenugreek seeds: a chronic study in non-insulin dependent diabetic patients. Alholva, Bird's Foot, Bockshornklee, Bockshornsame, Chandrika, Egypt Fenugreek, Fenogreco, Fenugrec, Foenugraeci Semen, Foenugreek, Greek Clover, Greek Hay, Greek Hay Seed, Hu Lu Ba, Medhika, Methi, Methika, Sénégrain, Sénégré, Trigonella, Trigonella Foenum, Trigonella foenum-graecum, Trigonella foenugraecum, Trigonelle, Woo Lu Bar. Indian J Physiol Pharmacol 2001;45(4):408-420. There are conflicting results regarding the effects of fenugreek on exercise performance. View abstract. Amin, A., Alkaabi, A., Al Falasi, S., and Daoud, S. A. Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer. Research shows that taking a specific fenugreek product (FenuLife, Frutarom Belgium) before the two biggest meals of the day reduces symptoms of heartburn. Songklanakarin J Sci Technol 2006;28(Suppl. Monitor your blood sugar closely. Taking 600 mg of a specific fenugreek seed extract (Libifem, Gencor Pacific Ltd.) each day seems to increase interest in sex in healthy younger women with a low sex drive. (Tokyo) 2006;52(4):287-292. 12-21-2005;11(47):7499-7507. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. View abstract. Rao A, Steels E, Beccaria G, Inder WJ, Vitetta L. Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Fenugreek might also slow blood clotting. Chem Biol.Interact. This survey is being conducted by the WebMD marketing sciences department. Handa, T., Yamaguchi, K., Sono, Y., and Yazawa, K. Effects of fenugreek seed extract in obese mice fed a high-fat diet. View abstract. View abstract. Effects of a purported aromatase and 5alpha-reductase inhibitor on hormone profiles in college-age men. Nutr J 2014;13:7. Nahas, R. and Moher, M. Complementary and alternative medicine for the treatment of type 2 diabetes. Phytother Res 2014;28(2):172-8. Taking 600 mg of a specific fenugreek seed extract (Testofen, Gencor Pacific Ltd) each day seems to improve ability and interest in sex in older men that have started to lose interest and in healthy younger men. J Assoc Physicians India 1994;42:33-5. Phytother Res. Pediatr Int 1999;41:108-9. A novel amino acid potentiator of insulin secretion. 6: 176-182. Cancer Lett. Taking fenugreek along with warfarin (Coumadin) might increase the chances of bruising and bleeding. View abstract. View abstract. Doses of at least 5 grams daily seems to help. Although not all side effects are known, fenugreek is thought to be possibly safe when taken for a short period of time. Phytother Res 1991;3(5):145-7. Microbiological diagnostic already, for this and other STEC/VTEC serotypes!]. Cicero, A. F., Derosa, G., and Gaddi, A. View abstract. Effect of fenugreek seeds on intravenous glucose disposition in non-insulin dependent diabetic patients. J Int Soc Sports Nutr 2008;5(1):11. View abstract. View abstract. Quiz: What Do You Know About Vitamin B12 Deficiency? View abstract. 2011; Ikeuchi, M., Yamaguchi, K., Koyama, T., Sono, Y., and Yazawa, K. Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. View abstract. View abstract. The postprandial hypoglycemic activity of fenugreek seed and seeds extract in type 2 diabetics: A pilot study. Thirunavukkarasu V and Anuradha CV. 2012;75(2):408-418. Wilborn C, Bushey B, Poole C, et al. View abstract. O'Mahony, R., Al Khtheeri, H., Weerasekera, D., Fernando, N., Vaira, D., Holton, J., and Basset, C. Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori. 2003;52(6):468-478. Z.Ernahrungswiss. Slivka, D., Cuddy, J., Hailes, W., Harger, S., and Ruby, B. Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding. "Hardening of the arteries" (atherosclerosis). View abstract. Narender, T., Puri, A., Shweta, Khaliq, T., Saxena, R., Bhatia, G., and Chandra, R. 4-hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. Hamden K, Jaouadi B, Carreau S, Aouidet A, El-Fazaa S, Gharbi N, Elfeki A. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Amino.Acids 2008;35(2):439-444. Cancer Biol.Ther 2009;8(3):272-278. Beutin, L. and Martin, A. Outbreak of Shiga toxin-producing Escherichia coli (STEC) O104:H4 infection in Germany causes a paradigm shift with regard to human pathogenicity of STEC strains. Gupta A, Gupta R, Lal B. Swaroop A, Jaipuriar AS, Gupta SK, Bagchi M, Kumar P, Preuss HG, Bagchi D. Efficacy of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst) in Polycystic Ovary Syndrome (PCOS). 2016 Nov;81:522-531. Mucinase in the management of non-insulin dependent diabetic subjects of herbal tea east Mediterr.Health 2000... Of BPH kandhare AD, Bodhankar SL, mohan V, et al ):41-8 Amzazi S. properties... Hepatotoxicity in male rats are also used to lower blood sugar and platelet aggregation in patients with to. ; 53 ( 2 ):162-174, E. Herbs for serum cholesterol:... Ageel AM, AlKharfy KM, Al-Suwayeh SA aggregation in patients with coronary artery.. 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