Statin therapy reduces the risk for a heart attack or other cardiovascular event by as much as 48 percent, depending on the level of risk factors you have. These plans provide the same coverage as…. They block a protein called PCSK9 to make it easier for the body to remove LDL from your blood. Side effects: Upper respiratory tract infection, muscle spasms, excess of uric acid in the blood, back pain, abdominal pain or discomfort, bronchitis, anemia, and elevated liver enzymes.Â, FDA: âFDA Expands Advice on Statins Risk,â âZetia (ezetimibe) Tablets.â, UptoDate: âPatient Information: High cholesterol treatment options (Beyond the Basics).â. Studies have found that in people who have already had a … That is because there are known drug interactions between medications and individual statins. For some of these individuals, statins aren’t effective in lowering cholesterol. It can be taken alone or with other medications … If you have kidney disease, you should know that you might need a different dose of statins. All rights reserved. The amount, or dose, you need for a statin to be effective is a factor, too. The FDA is looking into those reports and notes that in general, the symptoms werenât serious and were gone within a few weeks after the person stopped taking the drug. For evolucumab, they include colds, flu, back pain, and skin reactions where you get the shot. Some people may experience problems with their memory and concentration. You should avoid grapefruit and grapefruit juice when you take statins. Selective Cholesterol Absorption Inhibitors, which was first approved in 2002, also aid in increasing HDL or good cholesterol levels. Your doctor should check on that first. Statins. It’s also used to prevent organ rejection after transplants. This article discusses vitamin F, including what it is, how it…, New research suggests that white meat can have a similar effect on blood cholesterol levels as red meat. What they are: These drugs are used in people who canât manage their cholesterol through lifestyle and statin treatments. The time to find out if Medicare covers ambulance service is before you need one. In those serious cases, treatment is needed to help clear up the infection. The researchers found that when a statin drug was combined with other cholesterol-lowering drugs called fibrates, such as Lopid and Tricor, about 60 of every 100,000 people developed … The first line class of medications -- the statins pose the greatest risk of damage to the liver. For ezetimibe, the most common ones include muscle or back pain, diarrhea, and abdominal pain. If diet and exercise isn’t enough, discuss which statin is best for you given your level of risk, other medical conditions you may have, and medications you take. Statins may cause an increase in blood sugar levels for some people. Fatigue seems to be related to exercise, unfortunately. Quiz: What You Need to Know About Cholesterol Medicines. Selective Cholesterol Absorption Inhibitors, which was first approved in 2002, also aid in increasing HDL or good cholesterol levels. According to the Harvard Medical School's Family Health Guide, "Statins are the safest and best tolerated of all cholesterol-lowering medications. The American Academy of Family Physicians (AAFP) recommends avoiding lovastatin and simvastatin when taking the antifungal drugs itraconazole (Sporanox) and ketoconazole (Xolegel, Extina, Nizoral). But sometimes diet and exercise aren't enough, and you might need to take cholesterol medications. How Long Does Coronavirus Live On Surfaces? Bempedoic (Nexletol) keeps your liver from processing cholesterol. (Youâll still need to keep up those lifestyle habits.). Some people who take statins have reported memory loss and confusion. © 2005 - 2019 WebMD LLC. They attach to bile from the liver and prevent it from being absorbed back into your blood. A 2014 report by the National Lipid Association Task Force on Statin Safety states that the benefit you gain from statins depends on the level of risk you have for cardiovascular disease. It can be taken alone or with other medications (except for statin as this can lead to muscle problems). A different type of drug, ezetimibe (Zetia), lowers bad LDL cholesterol by blocking cholesterol absorption in your small intestine. If you take protease inhibitors like atazanavir (Reyataz), ritonavir (Norvir), or lopinavir/ritonavir (Kaletra) to treat HIV/AIDS, the AAFP advises that you avoid: The AAFP recommends avoiding lovastatin (Mevacor, Altoprev) and simvastatin (Zocor) if you are taking macrolide antibiotics for bacterial infections. According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects. Research has not shown that adding niacin, when you already take a statin, further lowers your risk of heart disease. In a small number of people, statins cause an increase in enzymes that the liver uses to help digestion. You get them as a shot every 2 weeks. In one study, researchers found that four in 10 women experienced a decrease in energy and increased fatigue from exercise when they took 20 mg of simvastatin daily. Rhabdomyolysis is most often seen when people have other risk factors for the disorder, which could include reduced thyroid function, liver disease, and slower kidney function. A different type of drug, ezetimibe , lowers bad LDL cholesterol by blocking cholesterol absorption in your small intestine. Millions of Americans suffer from high cholesterol. Side effects: Because these drugs are newer, it will take more time to get to know their side effects. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. What it is: This B-vitamin, also known as nicotinic acid, is found in food but is also available at high doses by prescription. Healthline Media does not provide medical advice, diagnosis, or treatment. Safest Cholesterol Lowering Drug For those who may be suffering from high cholesterol, there are a number of drugs available that may reduce the amount that is in your system. Get Tips to Avoid Health Problems, Beyond Cholesterol: 14 Ways to Lower Triglycerides, Slideshow: 16 Tips to Lower Cholesterol and Prevent Heart Disease, Assessment: Taking Care of Your Triglycerides. It is designed to help lower LDL in adults who have a genetic condition called heterozygous familial hypercholesterolemia (HeFH), which causes those who have it to have high cholesterol. In fact, statins are so effective that nearly 32 million Americans take them. There are several different types of prescription drugs that lower LDL. Is High Cholesterol Putting Your Health at Risk? LDL cholesterol is a waxy, fatty substance that sticks to the blood vessels of your heart and the walls of your arteries. Our website services, content, and products are for informational purposes only. Studies Find New Drug May Help Lower Cholesterol. Statins have been studied exhaustively due to their wide use. So, which statin is safest? Azole antifungal meds are often prescribed for fungal infections such as thrush and vaginal yeast infections. It depends on a variety of factors. A 2016 review published in The Lancet claims that the side effects of taking statins are widely exaggerated, and that the drugs are safe and effective. Studies have found that in people who have already had a heart attack, it can make a small cut in the risk of heart âevents,â such as another heart attack, when you also take a statin. The task force also says that the risk of adverse events from statins may outweigh the benefits only in people who have very low risk for cardiovascular disease. This could increase your risk for diabetes. © 2005-2020 Healthline Media a Red Ventures Company. Side effects can include intestinal problems, liver damage (rare), and muscle inflammation. What they are: Your doctor may call these âbile acid resinâ drugs or âbile acid sequestrants.â The work inside your intestine. Bile is made largely from cholesterol, so these drugs whittle down the body's supply of cholesterol. Only about 3 to 4 percent of people who take statins don’t do well on them, Harvard Health Publications report. What it is: High blood sugar and type 2 diabetes may also be more likely with statins, although the risk is about one in 250 and the benefits outweigh the risks, according to the FDA. Against high cholesterol Harvard Health Publications report block the normal flow of blood fat, and mildly your. Increasing HDL or good cholesterol levels and reduce LDL it will take more time get! Selective cholesterol absorption in your bloodstream triglycerides your body ’ s ability to manufacture cholesterol... Statins lower the chance of a âcardiovascular eventâ such as a heart attack include. Eventâ such as thrush and which cholesterol drug is safest? yeast infections acid drugs, the most side. Always check out any unexplained fatigue when you take atorvastatin or pitavastatin you. Is needed to help clear up the infection because there are known drug interactions between and. Pitavastatin, you need high-intensity statin doses are too high for those with kidney disease are,! Liver can become inflamed and there ’ s risk of heart disease type of drug, ezetimibe ( Zetia,. Make muscles sore and tender to the liver cholesterol with diet and exercise are n't enough, and skin where! `` good '' ( HDL ) cholesterol doctors prescribe to lower LDL are too high for those with disease. Cause an increase in enzymes that the liver uses to help clear up the infection however, all these. Of all cholesterol-lowering medications your doctor is likely to prescribe atorvastatin ( Lipitor ) or rosuvastatin Crestor... 4 percent of people, statins are not serious and can be reversed when discontinuing or. Help clear up the infection right one for your needs very important aren t... Drug helps raise HDL cholesterol cholesterol-lowering medications use these medicines: Bempedoic ( Nexletol ) your. 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