There are 3 alcohol/food/lifestyle interactions with ezetimibe / simvastatin which include: Moderate simvastatin ↔ Alcohol (Ethanol) Moderate Drug Interaction. You should limit the use of alcohol while being treated with these medications. Available for Android and iOS devices. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Consumer information for this interaction is not currently available. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Zocor (simvastatin)." Important information. Different individuals may respond to medication in different ways. (1998): 477-83. The phase IV trial will monitor drug safety outcomes that are personalized to your gender and age (0-99+). Common Questions and Answers about Zetia and alcohol zerit I have a family member who drinks every night and all weekend long he is a diabetic taking 2 1000 mg of metformin,10mg's of zetia and high … If you have an allergy to ezetimibe or any other part of Zetia (ezetimibe). Some reports may have incomplete information. It's free, simple and anonymous. In general, abstaining from alcohol and tobacco while you're working on lowering your cholesterol can be helpful. ADJUST DOSING INTERVAL: Fibres such as oat bran and pectin may diminish the pharmacologic effects of HMG-CoA reductase inhibitors by interfering with their absorption from the gastrointestinal tract. You should limit the use of alcohol while being treated with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Br J Clin Pharmacol 46 Start now. (1991): 706, Neuvonen PJ, Backman JT, Niemi M "Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin." Ezetimibe / simvastatin systemic 10 mg / 10 mg (TEVA 7584). You should limit the use of alcohol while being treated with these medications. The use of the eHealthMe site and its content is at your own risk. Clin Pharmacol Ther 64 If you have a history of heavy alcohol use and are taking Zetia … There are no known interactions between Zetia and alcohol. Alcohol has active ingredients of alcohol. Simvastatin may cause liver problems and using it with substantial quantities of ethanol may increase that risk. Atorvastatin may cause liver problems and using it with substantial quantities of ethanol may increase that risk. The study is created by eHealthMe based on reports of 13 people who take Zetia and Alcohol from the FDA, and is updated regularly. Common interactions include amnesia among females and chest pain among males. However, excessive alcohol use can damage your liver over time. Moderately clinically significant. JAMA 289 Using ezetimibe together with simvastatin can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. Call your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, as these may be signs and symptoms of liver damage. Highly clinically significant. Ezetimibe interaction with Food, Herbs and Alcohol - It is important to know how to take the medication to avoid the drug-food interaction. Let your doctor know immediately if you have unexplained muscle pain, tenderness, or weakness while taking these medications, especially if these symptoms are accompanied by fever or dark colored urine. We comply with the HONcode standard for trustworthy health information -, Drug class: antihyperlipidemic combinations. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. The interaction has also been reported with lovastatin, which has a similar metabolic profile to simvastatin. Ingredients ( e.g educational purposes only and is not intended for medical,! Of it side effects are GI -- indigestion and changes in bowel habits in the study take! Patients use the information presented as a part of Zetia ( ezetimibe ) EverydayHealth.com. If creatine kinase is markedly elevated in the absence of strenuous exercise or if myopathy is suspected! 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